School of Biomedical and Allied Health Sciences, University of Ghana, Ghana
Publications
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Original Article
Susceptibility of Clinical Isolates to Ceftriaxone-Sulbactam at the Ghana Police Hospital
Author(s): Daniel Kwame Afriyie*, Martha Gyansa-Lutterodt, George Asare, Rafik Mahama, Ohene-Mensah Prince and Manu Ofei
Abstract
Background: Ceftriaxone is the most common and widely used third generation cephalosporin empirically. Extensive use of ceftriaxone makes its highly prone to misutilization with increasing reports of microbial resistance globally, which sometimes linked to production of beta-lactamase. Combination therapy of ceftriaxone with sulbactam, a beta-lactamase inhibitor preserves its antibacterial activity. Periodic local antimicrobial surveillance of antibiotics is necessary to enhance their rational prescribing. Aim: The study aimed at determining susceptibility pattern of clinical isolates from various specimens to ceftriaxonesulbactam at the Ghana Police Hospital. Materials and Methods: Various types of clinical specimen (n=163) from patients were collected from October 2015 to February 2016. Microorganisms we..
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